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Heat shock protein 90 regulates soluble guanylyl cyclase maturation by a dual mechanism
The enzyme soluble guanylyl cyclase (sGC) is a heterodimer composed of an α subunit and a heme-containing β subunit. It participates in signaling by generating cGMP in response to nitric oxide (NO). Heme insertion into the β1 subunit of sGC (sGCβ) is critical for function, and heat shock protein 90...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721946/ https://ncbi.nlm.nih.gov/pubmed/31311859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009016 |
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