Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway

Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the therapeutic mechanisms and effects of the tetrapeptide Arg-Leu-Tyr-Glu (RLYE), a VEGFR2 in...

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Bibliographic Details
Published in:Biomol Ther (Seoul)
Main Authors: Park, Wonjin, Baek, Yi-Yong, Kim, Joohwan, Jo, Dong Hyun, Choi, Seunghwan, Kim, Jin Hyoung, Kim, Taesam, Kim, Suji, Park, Minsik, Kim, Ji Yoon, Won, Moo-Ho, Ha, Kwon-Soo, Kim, Jeong Hun, Kwon, Young-Guen, Kim, Young-Myeong
Format: Artigo
Language:Inglês
Published: The Korean Society of Applied Pharmacology 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720534/
https://ncbi.nlm.nih.gov/pubmed/31042676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2019.041
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