NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function

Endothelial progenitor cell (EPC) dysfunction impairs vascular function and remodeling in inflammation-associated diseases, including preeclampsia. However, the underlying mechanism of this inflammation-induced dysfunction remains unclear. In the present study, we found increases in TNF-α and miR-31...

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Publicado en:Exp Mol Med
Autores principales: Kim, Ji-Hee, Kim, Ji-Yoon, Park, Minsik, Kim, Suji, Kim, Taesam, Kim, Joohwan, Choi, Seunghwan, Park, Wonjin, Hwang, Jong Yun, Choe, Jongseon, Ha, Kwon-Soo, Won, Moo-Ho, Ryoo, Sungwoo, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080610/
https://ncbi.nlm.nih.gov/pubmed/32770080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0478-x
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