Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis

Heme oxygenase-1-derived carbon monoxide prevents inflammatory vascular disorders. To date, there is no clear evidence that HO-1/CO prevents endothelial dysfunction associated with the downregulation of endothelial NO synthesis in human endothelial cells stimulated with TNF-α. Here, we found that th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Mol Med
Main Authors: Choi, Seunghwan, Kim, Joohwan, Kim, Ji-Hee, Lee, Dong-Keon, Park, Wonjin, Park, Minsik, Kim, Suji, Hwang, Jong Yun, Won, Moo-Ho, Choi, Yoon Kyung, Ryoo, Sungwoo, Ha, Kwon-Soo, Kwon, Young-Guen, Kim, Young-Myeong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704195/
https://ncbi.nlm.nih.gov/pubmed/29170479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.193
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