Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily isolated and autologous to avoid immune rejection. We transdifferentiated (TD) human fibroblasts into tumor-homing early-stage induced NSCs (h-iNS...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Bagó, Juli R., Okolie, Onyi, Dumitru, Raluca, Ewend, Matthew G., Parker, Joel S., Werff, Ryan Vander, Underhill, T. Michael, Schmid, Ralf S., Miller, C. Ryan, Hingtgen, Shawn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719790/
https://ncbi.nlm.nih.gov/pubmed/28148846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6510
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