Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily isolated and autologous to avoid immune rejection. We transdifferentiated (TD) human fibroblasts into tumor-homing early-stage induced NSCs (h-iNS...

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Pubblicato in:Sci Transl Med
Autori principali: Bagó, Juli R., Okolie, Onyi, Dumitru, Raluca, Ewend, Matthew G., Parker, Joel S., Werff, Ryan Vander, Underhill, T. Michael, Schmid, Ralf S., Miller, C. Ryan, Hingtgen, Shawn D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719790/
https://ncbi.nlm.nih.gov/pubmed/28148846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6510
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