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Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily isolated and autologous to avoid immune rejection. We transdifferentiated (TD) human fibroblasts into tumor-homing early-stage induced NSCs (h-iNS...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Bagó, Juli R., Okolie, Onyi, Dumitru, Raluca, Ewend, Matthew G., Parker, Joel S., Werff, Ryan Vander, Underhill, T. Michael, Schmid, Ralf S., Miller, C. Ryan, Hingtgen, Shawn D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719790/
https://ncbi.nlm.nih.gov/pubmed/28148846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6510
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