Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma

Transdifferentiation (TD) is a recent advancement in somatic cell reprogramming. The direct conversion of TD eliminates the pluripotent intermediate state to create cells that are ideal for personalized cell therapy. Here we provide evidence that TD-derived induced neural stem cells (iNSCs) are an e...

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Publicado no:Nat Commun
Main Authors: Bagó, Juli R., Alfonso-Pecchio, Adolfo, Okolie, Onyi, Dumitru, Raluca, Rinkenbaugh, Amanda, Baldwin, Albert S., Miller, C. Ryan, Magness, Scott T., Hingtgen, Shawn D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740908/
https://ncbi.nlm.nih.gov/pubmed/26830441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10593
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