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Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma

Engineered stem cell (SC)-based therapy holds enormous promise for treating the incurable brain cancer glioblastoma (GBM). Retaining the cytotoxic SCs in the surgical cavity after GBM resection is one of the greatest challenges to this approach. Here, we describe a biocompatible electrospun nanofibr...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Bagó, Juli R., Pegna, Guillaume J., Okolie, Onyi, Mohiti-Asli, Mahsa, Loboa, Elizabeth G., Hingtgen, Shawn D.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376347/
https://ncbi.nlm.nih.gov/pubmed/27016620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.03.008
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