Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

Engineered neural stem cells (NSCs) are a promising approach to treating glioblastoma (GBM). The ideal NSC drug carrier for clinical use should be easily isolated and autologous to avoid immune rejection. We transdifferentiated (TD) human fibroblasts into tumor-homing early-stage induced NSCs (h-iNS...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Bagó, Juli R., Okolie, Onyi, Dumitru, Raluca, Ewend, Matthew G., Parker, Joel S., Werff, Ryan Vander, Underhill, T. Michael, Schmid, Ralf S., Miller, C. Ryan, Hingtgen, Shawn D.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719790/
https://ncbi.nlm.nih.gov/pubmed/28148846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6510
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