Integrated in vivo multi-omics analysis identifies p21-activated kinase signaling as a driver of colitis

Inflammatory bowel disease (IBD) is a chronic disorder of the gastrointestinal tract. The molecular mechanisms underlying IBD are poorly characterized and treatment options are limited. To gain insight into the pathogenesis of chronic colonic inflammation (colitis), we performed a multi-omic analysi...

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Dades bibliogràfiques
Publicat a:Sci Signal
Autors principals: Lyons, Jesse, Brubaker, Douglas K., Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Strasser, Samantha Dale, Suarez-Lopez, Lucia, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Lauffenburger, Douglas A., Haigis, Kevin M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719711/
https://ncbi.nlm.nih.gov/pubmed/29487189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan3580
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