Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

One gene can give rise to many functionally distinct proteoforms, each of which has a characteristic molecular mass. Top-down mass spectrometry enables the analysis of intact proteins and proteoforms. Here members of the Consortium for Top-Down Proteomics provide a decision tree that guides research...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Methods
Egile Nagusiak: Donnelly, Daniel P., Rawlins, Catherine M., DeHart, Caroline J., Fornelli, Luca, Schachner, Luis F., Lin, Ziqing, Lippens, Jennifer L., Aluri, Krishna C., Sarin, Richa, Chen, Bifan, Lantz, Carter, Jung, Wonhyeuk, Johnson, Kendall R., Koller, Antonius, Wolff, Jeremy J., Campuzano, Iain D. G., Auclair, Jared R., Ivanov, Alexander R., Whitelegge, Julian P., Paša-Tolić, Ljiljana, Chamot-Rooke, Julia, Danis, Paul O., Smith, Lloyd M., Tsybin, Yury O., Loo, Joseph A., Ge, Ying, Kelleher, Neil L., Agar, Jeffrey N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group US 2019
Gaiak:
Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719561/
https://ncbi.nlm.nih.gov/pubmed/31249407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0457-0
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