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A mass graph-based approach for the identification of modified proteoforms using top-down tandem mass spectra

MOTIVATION: Although proteomics has rapidly developed in the past decade, researchers are still in the early stage of exploring the world of complex proteoforms, which are protein products with various primary structure alterations resulting from gene mutations, alternative splicing, post-translatio...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Kou, Qiang, Wu, Si, Tolić, Nikola, Paša-Tolić, Ljiljana, Liu, Yunlong, Liu, Xiaowen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860502/
https://ncbi.nlm.nih.gov/pubmed/28453668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw806
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