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A graph-based approach for proteoform identification and quantification using top-down homogeneous multiplexed tandem mass spectra

BACKGROUND: Top-down homogeneous multiplexed tandem mass (HomMTM) spectra are generated from modified proteoforms of the same protein with different post-translational modification patterns. They are frequently observed in the analysis of ultramodified proteins, some proteoforms of which have simila...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zhu, Kaiyuan, Liu, Xiaowen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101081/
https://ncbi.nlm.nih.gov/pubmed/30367573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2273-4
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