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Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

Amino acid starvation in Escherichia coli activates the enzymatic activity of the stringent factor RelA, leading to accumulation of the alarmone nucleotide (p)ppGpp. The alarmone acts as an intercellular messenger to regulate transcription, translation and metabolism to mediate bacterial stress adap...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Turnbull, Kathryn Jane, Dzhygyr, Ievgen, Lindemose, Søren, Hauryliuk, Vasili, Roghanian, Mohammad
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719525/
https://ncbi.nlm.nih.gov/pubmed/31507571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01966
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