TWEAK/Fn14 Is Overexpressed in Crohn’s Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune Pathways

BACKGROUND & AIMS: Crohn’s disease (CD) is a debilitating inflammatory disorder that affects more than 1.6 million people in North America alone. Members of the tumor necrosis factor superfamily are key regulators of intestinal inflammation; specifically, tumor necrosis factor–like weak inducer...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Di Martino, Luca, Osme, Abdullah, Kossak-Gupta, Sarah, Pizarro, Theresa T., Cominelli, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718944/
https://ncbi.nlm.nih.gov/pubmed/31181286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.05.009
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