TWEAK/Fn14 Is Overexpressed in Crohn’s Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune Pathways

BACKGROUND & AIMS: Crohn’s disease (CD) is a debilitating inflammatory disorder that affects more than 1.6 million people in North America alone. Members of the tumor necrosis factor superfamily are key regulators of intestinal inflammation; specifically, tumor necrosis factor–like weak inducer...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Di Martino, Luca, Osme, Abdullah, Kossak-Gupta, Sarah, Pizarro, Theresa T., Cominelli, Fabio
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718944/
https://ncbi.nlm.nih.gov/pubmed/31181286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.05.009
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