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FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements
The bile acid-activated nuclear receptor, FXR (NR1H4), has been implicated in the control of lipid and energy metabolism, but its role in fat tissue, where it is moderately expressed, is not understood. In view of the recent development of FXR-targeting therapeutics for treatment of human metabolic...
Zapisane w:
| Wydane w: | J Lipid Res |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718433/ https://ncbi.nlm.nih.gov/pubmed/31253637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094508 |
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