FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements

The bile acid-activated nuclear receptor, FXR (NR1H4), has been implicated in the control of lipid and energy metabolism, but its role in fat tissue, where it is moderately expressed, is not understood. In view of the recent development of FXR-targeting therapeutics for treatment of human metabolic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Lipid Res
Prif Awduron: van Zutphen, Tim, Stroeve, Johanna H. M., Yang, Jiufang, Bloks, Vincent W., Jurdzinski, Angelika, Roelofsen, Han, Huijkman, Nicolette C. A., van Dijk, Theo H., Vonk, Roel J., van Deursen, Jan, Staels, Bart, Groen, Albert K., Kuipers, Folkert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718433/
https://ncbi.nlm.nih.gov/pubmed/31253637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094508
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg