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miR-146a Deficiency Accelerates Hepatic Inflammation Without Influencing Diet-induced Obesity in Mice

miR-146a, an anti-inflammatory microRNA, is shown to be a negative regulator of adipocyte inflammation. However, the functional contribution of miR-146a in the development of obesity is not defined. In order to determine whether miR-146a influences diet-induced obesity, mice that were either wild ty...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Javidan, Aida, Jiang, Weihua, Okuyama, Michihiro, Thiagarajan, Devi, Yang, Lihua, Moorleghen, Jessica J., Muniappan, Latha, Subramanian, Venkateswaran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718417/
https://ncbi.nlm.nih.gov/pubmed/31477775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49090-4
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