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Mst1/2 Kinases Inhibitor, XMU-MP-1, Attenuates Angiotensin II-Induced Ascending Aortic Expansion in Hypercholesterolemic Mice

Background: Ascending and abdominal aortic aneurysms (AAs) are asymptomatic, permanent dilations of the aorta with surgical intervention as the currently available therapy. Hippo-Yap signaling cascade plays a critical role in stem cell self-renewal, tissue regeneration and organ size control. By usi...

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Detalhes bibliográficos
Publicado no:Circ Rep
Main Authors: Okuyama, Michihiro, Jiang, Weihua, Yang, Lihua, Subramanian, Venkateswaran
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Circulation Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099673/
https://ncbi.nlm.nih.gov/pubmed/34007939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1253/circrep.CR-20-0104
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