The Effects of a Single Oral Dose of Pyridoxine on Alpha-Aminoadipic Semialdehyde, Piperideine-6-Carboxylate, Pipecolic Acid, and Alpha-Aminoadipic Acid Levels in Pyridoxine-Dependent Epilepsy

Purpose: To evaluate the effects of a single oral dose of pyridoxine on lysine metabolites including α-aminoadipic semialdehyde (a-AASA), piperideine-6-carboxylate (P6C), the sum of AASA and P6C (AASA-P6C), pipecolic acid (PA), and α-aminoadipic acid (α-AAA) in PDE patients. Methods: The lysine meta...

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Bibliographic Details
Published in:Front Pediatr
Main Authors: Wang, Junjuan, Xue, Jiao, Gong, Pan, Wu, Minhang, Yang, Wenshuang, Jiang, Shiju, Wu, Ye, Jiang, Yuwu, Zhang, Yuehua, Yuzyuk, Tatiana, Li, Hong, Yang, Zhixian
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pediatrics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718124/
https://ncbi.nlm.nih.gov/pubmed/31508398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2019.00337
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