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Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.

The first two steps in the mammalian lysine-degradation pathway are catalyzed by lysine-ketoglutarate reductase and saccharopine dehydrogenase, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Defects in one or both of these activities result in familial hyperly...

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Autors principals: Sacksteder, K A, Biery, B J, Morrell, J C, Goodman, B K, Geisbrecht, B V, Cox, R P, Gould, S J, Geraghty, M T
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378037/
https://ncbi.nlm.nih.gov/pubmed/10775527
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