Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice

Seasonal influenza virus infections cause significant morbidity and mortality every year. Annual influenza virus vaccines are effective but only when well matched with circulating strains. Therefore, there is an urgent need for better vaccines that induce broad protection against drifted seasonal an...

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Veröffentlicht in:Vaccine
Hauptverfasser: Asthagiri Arunkumar, Guha, McMahon, Meagan, Pavot, Vincent, Aramouni, Mario, Ioannou, Andriani, Lambe, Teresa, Gilbert, Sarah, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717082/
https://ncbi.nlm.nih.gov/pubmed/31399277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.07.095
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