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Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases

Terpene synthases are capable of mediating complex reactions, but fundamentally simply catalyze lysis of allylic diphosphate esters with subsequent deprotonation. Even with the initially generated tertiary carbocation this offers a variety of product outcomes, and deprotonation further can be preced...

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Detaylı Bibliyografya
Yayımlandı:Metab Eng
Asıl Yazarlar: Jia, Meirong, Mishra, Sambit K., Tufts, Samuel, Jernigan, Robert L., Peters, Reuben J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717049/
https://ncbi.nlm.nih.gov/pubmed/31220664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2019.06.008
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