A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1

BACKGROUND: The RTK/PI3K/AKT pathway plays key roles in the development and progression of many cancers, including GBM. As a regulatory molecule and a potential drug target, the oncogenic role of AKT has been substantially studied. Three isoforms of AKT have been identified, including AKT1, AKT2 and...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Mol Cancer
Glavni autori: Xia, Xin, Li, Xixi, Li, Fanying, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Huang, Nunu, Yang, Xuesong, Xiao, Feizhe, Liu, Dawei, Yang, Lixuan, Zhang, Nu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716823/
https://ncbi.nlm.nih.gov/pubmed/31470874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1056-5
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items