Llwytho...

Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance

Recent advances in single cell technology have enabled dissection of cellular heterogeneity in great detail. However, analysis of single cell DNA sequencing data remains challenging due to bias and artifacts that arise during DNA extraction and whole-genome amplification, including allelic imbalance...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Luquette, Lovelace J., Bohrson, Craig L., Sherman, Max A., Park, Peter J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715686/
https://ncbi.nlm.nih.gov/pubmed/31467286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11857-8
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