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Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance
Recent advances in single cell technology have enabled dissection of cellular heterogeneity in great detail. However, analysis of single cell DNA sequencing data remains challenging due to bias and artifacts that arise during DNA extraction and whole-genome amplification, including allelic imbalance...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6715686/ https://ncbi.nlm.nih.gov/pubmed/31467286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11857-8 |
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