Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels

Brain-derived neurotrophic factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its Ntrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of several neurological and neurodegenerative disorder...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Tomassoni-Ardori, Francesco, Fulgenzi, Gianluca, Becker, Jodi, Barrick, Colleen, Palko, Mary Ellen, Kuhn, Skyler, Koparde, Vishal, Cam, Maggie, Yanpallewar, Sudhirkumar, Oberdoerffer, Shalini, Tessarollo, Lino
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2019
विषय:
Neuroscience
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715404/
https://ncbi.nlm.nih.gov/pubmed/31429825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49673
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