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PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice
Palmitic acid esters of hydroxy stearic acids (PAHSAs) are endogenous antidiabetic and antiinflammatory lipids. Here, we show that PAHSAs protect against type 1 diabetes (T1D) and promote β cell survival and function. Daily oral PAHSA administration to nonobese diabetic (NOD) mice delayed the onset...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6715391/ https://ncbi.nlm.nih.gov/pubmed/31380811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122445 |
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