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PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

Palmitic acid esters of hydroxy stearic acids (PAHSAs) are bioactive lipids with antiinflammatory and antidiabetic effects. PAHSAs reduce ambient glycemia and improve glucose tolerance and insulin sensitivity in insulin-resistant aged chow- and high-fat diet–fed (HFD-fed) mice. Here, we aimed to det...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Zhou, Peng, Santoro, Anna, Peroni, Odile D., Nelson, Andrew T., Saghatelian, Alan, Siegel, Dionicio, Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763232/
https://ncbi.nlm.nih.gov/pubmed/31449056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127092
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