PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

Palmitic acid esters of hydroxy stearic acids (PAHSAs) are bioactive lipids with antiinflammatory and antidiabetic effects. PAHSAs reduce ambient glycemia and improve glucose tolerance and insulin sensitivity in insulin-resistant aged chow- and high-fat diet–fed (HFD-fed) mice. Here, we aimed to det...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhou, Peng, Santoro, Anna, Peroni, Odile D., Nelson, Andrew T., Saghatelian, Alan, Siegel, Dionicio, Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763232/
https://ncbi.nlm.nih.gov/pubmed/31449056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127092
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