PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

Palmitic acid esters of hydroxy stearic acids (PAHSAs) are bioactive lipids with antiinflammatory and antidiabetic effects. PAHSAs reduce ambient glycemia and improve glucose tolerance and insulin sensitivity in insulin-resistant aged chow- and high-fat diet–fed (HFD-fed) mice. Here, we aimed to det...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Zhou, Peng, Santoro, Anna, Peroni, Odile D., Nelson, Andrew T., Saghatelian, Alan, Siegel, Dionicio, Kahn, Barbara B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763232/
https://ncbi.nlm.nih.gov/pubmed/31449056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127092
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