PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

Palmitic acid esters of hydroxy stearic acids (PAHSAs) are bioactive lipids with antiinflammatory and antidiabetic effects. PAHSAs reduce ambient glycemia and improve glucose tolerance and insulin sensitivity in insulin-resistant aged chow- and high-fat diet–fed (HFD-fed) mice. Here, we aimed to det...

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Vydáno v:J Clin Invest
Hlavní autoři: Zhou, Peng, Santoro, Anna, Peroni, Odile D., Nelson, Andrew T., Saghatelian, Alan, Siegel, Dionicio, Kahn, Barbara B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763232/
https://ncbi.nlm.nih.gov/pubmed/31449056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127092
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