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GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects

Adipose tissue (AT) regulates systemic insulin sensitivity through multiple mechanisms, and alterations in de novo lipogenesis appear to contribute. Mice overexpressing GLUT4 in adipocytes (AG4OX) have elevated AT lipogenesis and enhanced glucose tolerance despite being obese and having elevated cir...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Moraes-Vieira, Pedro M., Saghatelian, Alan, Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915575/
https://ncbi.nlm.nih.gov/pubmed/27288004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0221
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