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Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient derived xenografts in vivo

Overexpression or activation of AKT is very well known to control cell growth, survival and gene expression in solid tumors. Oridonin, an inflammatory medical and diterpenoid compound isolated from Rabdosia rubescens, has exhibited various pharmacological and physiological properties, including anti...

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書目詳細資料
發表在:Mol Cancer Ther
Main Authors: Song, Mengqiu, Liu, Xuejiao, Liu, Kangdong, Zhao, Ran, Huang, Hai, Shi, Yuanyuan, Zhang, Man, Zhou, Silei, Xie, Hua, Chen, Hanyong, Li, Yin, Zheng, Yan, Wu, Qiong, Liu, Fangfang, Li, Enmin, Bode, Ann M., Dong, Zigang, Lee, Mee-Hyun
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715294/
https://ncbi.nlm.nih.gov/pubmed/29695636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0823
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