FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma

Fibroblast growth factor receptor (FGFR) 2 and its downstream signaling cascades, PI3K/AKT/mTOR is playing an important role in cell survival and proliferations. In this study, we firstly found that picrasidine Q (PQ), an alkaloid component extracted from Angelica keiskei species, has the capacity o...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Shi, Yuanyuan, Liu, Xuejiao, Fredimoses, Mangaladoss, Song, Mengqiu, Chen, Hanyong, Liu, Kangdong, Lee, Mee-Hyun, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954433/
https://ncbi.nlm.nih.gov/pubmed/28857247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26385
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