Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

Esophageal cancer, a leading cause of cancer death worldwide, is associated with abnormal activation of the AKT signaling pathway. Xanthohumol, a prenylated flavonoid tested in clinical trials, is reported to exert anti‐diabetes, anti‐inflammation and anticancer activities. However, the mechanisms u...

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Dades bibliogràfiques
Publicat a:Int J Cancer
Autors principals: Liu, Xuejiao, Song, Mengqiu, Wang, Penglei, Zhao, Ran, Chen, Hanyong, Zhang, Man, Shi, Yuanyuan, Liu, Kangdong, Liu, Fangfang, Yang, Ran, Li, Enmin, Bode, Ann M., Dong, Zigang, Lee, Mee‐Hyun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Cancer Therapy and Prevention
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618024/
https://ncbi.nlm.nih.gov/pubmed/30887517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32285
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