Reversal of Factor Xa Inhibitors by Andexanet Alfa May Increase Thrombogenesis Compared to Pretreatment Values

Recombinant coagulation factor Xa (FXa), inactivated Zh-zo, also known as andexanet alfa (AA), is a modified version of human FXa that has been developed to neutralize FXa inhibitors. We studied the reversal effect of AA for these inhibitors in various anticoagulant and thrombin generation (TG) assa...

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Publicat a:Clin Appl Thromb Hemost
Autors principals: Siddiqui, Fakiha, Tafur, Alfonso, Ramacciotti, Lorenzo Storino, Jeske, Walter, Hoppensteadt, Debra, Ramacciotti, Eduardo, Iqbal, Omer, Fareed, Jawed
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714992/
https://ncbi.nlm.nih.gov/pubmed/31298056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029619863493
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