Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

The currently available oral anti-Xa agents are claimed to produce their anticoagulant and antithrombotic effects solely by the inhibition of factor Xa. This study profiled various anti-Xa drugs in routinely used laboratory assays to demonstrate that their effects are not solely related to the anti-...

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Bibliographic Details
Published in:Clin Appl Thromb Hemost
Main Authors: Siddiqui, Fakiha, Hoppensteadt, Debra, Jeske, Walter, Iqbal, Omer, Tafur, Alfonso, Fareed, Jawed
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714936/
https://ncbi.nlm.nih.gov/pubmed/31088146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029619847524
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