Assay-Based Differentiation in the Neutralization Profile of Unfractionated Heparin, Enoxaparin, and Fondaparinux by Andexanet Alfa

Andexanet alfa is a recombinant factor Xa decoy protein, designed to reverse bleeding associated with oral anti-Xa agents. Andexanet alfa is also reported to neutralize the effects of heparin-related drugs. This study focused on the neutralization profiles of unfractionated heparin (UFH), enoxaparin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Appl Thromb Hemost
Prif Awduron: Siddiqui, Fakiha, Tafur, Alfonso, Bontekoe, Emily, Iqbal, Omer, Jeske, Walter, Mehrotra, Siddharth, Hoppensteadt, Debra, Ramacciotti, Eduardo, Fareed, Jawed
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098205/
https://ncbi.nlm.nih.gov/pubmed/31914798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029619895120
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