Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: implications for therapeutic targeting of astroglia

The neuropathogenesis of HIV associated neurocognitive disorders (HAND) involves disruption of in mitochondrial homeostasis and increased neuroinflammation. However, it is unknown if alterations in mitochondrial biogenesis in the brain underlie the neuropathogenesis of HAND. In this study, neuropath...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Swinton, Mary K., Carson, Aliyah, Telese, Francesca, Sanchez, Ana B., Soontornniyomkij, Benchawanna, Rad, Leila, Batki, Isabella, Quintanilla, Brandi, Perez-Santiago, Josue, Achim, Cristian L., Letendre, Scott, Ellis, Ronald J., Grant, Igor, Murphy, Anne N., Fields, Jerel Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714553/
https://ncbi.nlm.nih.gov/pubmed/31238091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104502
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