Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: implications for therapeutic targeting of astroglia

The neuropathogenesis of HIV associated neurocognitive disorders (HAND) involves disruption of in mitochondrial homeostasis and increased neuroinflammation. However, it is unknown if alterations in mitochondrial biogenesis in the brain underlie the neuropathogenesis of HAND. In this study, neuropath...

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Bibliografske podrobnosti
izdano v:Neurobiol Dis
Main Authors: Swinton, Mary K., Carson, Aliyah, Telese, Francesca, Sanchez, Ana B., Soontornniyomkij, Benchawanna, Rad, Leila, Batki, Isabella, Quintanilla, Brandi, Perez-Santiago, Josue, Achim, Cristian L., Letendre, Scott, Ellis, Ronald J., Grant, Igor, Murphy, Anne N., Fields, Jerel Adam
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714553/
https://ncbi.nlm.nih.gov/pubmed/31238091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104502
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