Alterations in brain TREM2 and Amyloid-β levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy

Neuroinflammation is a common pathological correlate of HIV-associated neurocognitive disorders (HAND) in individuals on antiretroviral therapy (ART). Triggering receptor-expressed on myeloid cells 2 (TREM2) regulates neuroinflammation, clears extracellular Amyloid (A)-β, surveys for damaged neurons...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Fields, Jerel Adam, Spencer, Brian, Swinton, Mary, Qvale, Emma Martine, Marquine, María J., Alexeeva, Arina, Gough, Sarah, Soontornniyomkij, Benchawanna, Valera, Elvira, Masliah, Eliezer, Achim, Cristian L., Desplats, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310632/
https://ncbi.nlm.nih.gov/pubmed/30152135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14582
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