Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

Understanding transcriptional changes engaged in stress resilience may reveal novel antidepressant targets. Here, we use gene co-expression analysis of RNA-sequencing data from brains of resilient mice to identify a gene network that is unique to resilience. Zfp189, which encodes a previously unstud...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nat Neurosci
المؤلفون الرئيسيون: Lorsch, Zachary S., Hamilton, Peter J., Ramakrishnan, Aarthi, Parise, Eric M., Salery, Marine, Wright, William J., Lepack, Ashley E., Mews, Philipp, Issler, Orna, McKenzie, Andrew, Zhou, Xianxiao, Parise, Lyonna F., Pirpinias, Stephen T., Torres, Idelisse Ortiz, Kronman, Hope G., Montgomery, Sarah E., Loh, Yong-Hwee Eddie, Labonté, Benoit, Conkey, Andrew, Symonds, Ann E., Neve, Rachael L., Turecki, Gustavo, Maze, Ian, Dong, Yan, Zhang, Bin, Shen, Li, Bagot, Rosemary C., Nestler, Eric J.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2019
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713580/
https://ncbi.nlm.nih.gov/pubmed/31427770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0462-8
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