Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Most people exposed to stress do not develop depression. Animal models have shown that stress resilience is an active state that requires broad transcriptional adaptations, but how this homeostatic process is regulated remains poorly understood. In this study, we analyze upstream regulators of genes...

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Argitaratua izan da:Nat Commun
Egile Nagusiak: Lorsch, Zachary S., Loh, Yong-Hwee Eddie, Purushothaman, Immanuel, Walker, Deena M., Parise, Eric M., Salery, Marine, Cahill, Michael E., Hodes, Georgia E., Pfau, Madeline L., Kronman, Hope, Hamilton, Peter J., Issler, Orna, Labonté, Benoit, Symonds, Ann E., Zucker, Matthew, Zhang, Tie Yuan, Meaney, Michael J., Russo, Scott J., Shen, Li, Bagot, Rosemary C., Nestler, Eric J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856766/
https://ncbi.nlm.nih.gov/pubmed/29549264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03567-4
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