Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior

Human major depressive disorder (MDD), along with related mood disorders, is among the world’s greatest public health concerns; however, its pathophysiology remains poorly understood. Persistent changes in gene expression are known to promote physiological aberrations implicated in MDD. More recentl...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lepack, Ashley E., Bagot, Rosemary C., Peña, Catherine J., Loh, Yong-Hwee E., Farrelly, Lorna A., Lu, Yang, Powell, Samuel K., Lorsch, Zachary S., Issler, Orna, Cates, Hannah M., Tamminga, Carol A., Molina, Henrik, Shen, Li, Nestler, Eric J., Allis, C. David, Maze, Ian
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098673/
https://ncbi.nlm.nih.gov/pubmed/27791098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608270113
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