Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior

Human major depressive disorder (MDD), along with related mood disorders, is among the world’s greatest public health concerns; however, its pathophysiology remains poorly understood. Persistent changes in gene expression are known to promote physiological aberrations implicated in MDD. More recentl...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lepack, Ashley E., Bagot, Rosemary C., Peña, Catherine J., Loh, Yong-Hwee E., Farrelly, Lorna A., Lu, Yang, Powell, Samuel K., Lorsch, Zachary S., Issler, Orna, Cates, Hannah M., Tamminga, Carol A., Molina, Henrik, Shen, Li, Nestler, Eric J., Allis, C. David, Maze, Ian
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098673/
https://ncbi.nlm.nih.gov/pubmed/27791098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608270113
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