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Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1

T-cell engaging bispecific antibodies (biAbs) can mediate potent and specific tumor cell eradication in liquid cancers. Substantial effort has been invested in expanding this concept to solid cancers. To explore their utility in the treatment of ovarian cancer, we built a set of asymmetric biAbs in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Qi, Junpeng, Hymel, David, Nelson, Christopher G., Burke, Terrence R., Rader, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712926/
https://ncbi.nlm.nih.gov/pubmed/31497024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01994
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