Chemically Programmed Bispecific Antibodies in Diabody Format

Chemically programmed bispecific antibodies (biAbs) endow target cell-binding small molecules with the ability to recruit and activate effector cells of the immune system. Here we report a platform of chemically programmed biAbs aimed at redirecting cytotoxic T cells to eliminate cancer cells. Two d...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Walseng, Even, Nelson, Christopher G., Qi, Junpeng, Nanna, Alex R., Roush, William R., Goswami, Rajib K., Sinha, Subhash. C., Burke, Terrence R., Rader, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016699/
https://ncbi.nlm.nih.gov/pubmed/27445334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745588
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