Chemically Programmed Bispecific Antibodies in Diabody Format

Chemically programmed bispecific antibodies (biAbs) endow target cell-binding small molecules with the ability to recruit and activate effector cells of the immune system. Here we report a platform of chemically programmed biAbs aimed at redirecting cytotoxic T cells to eliminate cancer cells. Two d...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Walseng, Even, Nelson, Christopher G., Qi, Junpeng, Nanna, Alex R., Roush, William R., Goswami, Rajib K., Sinha, Subhash. C., Burke, Terrence R., Rader, Christoph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016699/
https://ncbi.nlm.nih.gov/pubmed/27445334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745588
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki