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Chemically Programmed Bispecific Antibodies That Recruit and Activate T Cells
Bispecific antibodies (biAbs) that mediate cytotoxicity by recruiting and activating endogenous immune cells are an emerging class of next-generation antibody therapeutics. Of particular interest are biAbs of relatively small size (∼50 kDa) that can redirect cytotoxic T cells through simultaneous bi...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436515/ https://ncbi.nlm.nih.gov/pubmed/22761439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384594 |
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