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The Effect of Phosphatidylserine on a pH-Responsive Peptide Is Defined by Its Noninserting End
The acidity-triggered rational membrane (ATRAM) peptide was designed to target acidic diseases such as cancer. An acidic extracellular medium, such as that found in aggressive tumors, drives the protonation of the glutamic acids in ATRAM, leading to the membrane translocation of its C-terminus and t...
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| Publié dans: | Biophys J |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712489/ https://ncbi.nlm.nih.gov/pubmed/31400916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.023 |
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