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The Effect of Phosphatidylserine on a pH-Responsive Peptide Is Defined by Its Noninserting End
The acidity-triggered rational membrane (ATRAM) peptide was designed to target acidic diseases such as cancer. An acidic extracellular medium, such as that found in aggressive tumors, drives the protonation of the glutamic acids in ATRAM, leading to the membrane translocation of its C-terminus and t...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712489/ https://ncbi.nlm.nih.gov/pubmed/31400916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.023 |
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