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Determination of the Membrane Translocation pK of the pH-Low Insertion Peptide
The pH-low insertion peptide (pHLIP) is a leading peptide technology to target the extracellular acidosis that characterizes solid tumors. The pHLIP binds to lipid membranes, and responds to acidification by undergoing a coupled folding/membrane insertion process. In the final transmembrane state, t...
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| Publicado en: | Biophys J |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Biophysical Society
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567424/ https://ncbi.nlm.nih.gov/pubmed/28834723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.065 |
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