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Determination of the Membrane Translocation pK of the pH-Low Insertion Peptide

The pH-low insertion peptide (pHLIP) is a leading peptide technology to target the extracellular acidosis that characterizes solid tumors. The pHLIP binds to lipid membranes, and responds to acidification by undergoing a coupled folding/membrane insertion process. In the final transmembrane state, t...

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Publicat a:Biophys J
Autors principals: Scott, Haden L., Westerfield, Justin M., Barrera, Francisco N.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567424/
https://ncbi.nlm.nih.gov/pubmed/28834723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.065
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